Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses

被引：9

作者：

Khan, Maliha ^{[1
]}

Nizami, Sobia ^{[2
]}

Mirrakhimov, Aibek E. ^{[1
]}

Maughan, Benjamin ^{[3
]}

Bishop, Justin A. ^{[3
]}

Sharfman, William H. ^{[3
]}

机构：

[1] Presence St Joseph Hosp, Dept Internal Med, 2900 N Lake Shore Dr, Chicago, IL 60657 USA

[2] Aga Khan Univ, Dept Med, Karachi 74800, Pakistan

[3] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD 21287 USA

来源：

CASE REPORTS IN MEDICINE | 2014年 / 2014卷

关键词：

D O I：

10.1155/2014/874719

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Small cell neuroendocrine carcinoma of the paranasal sinuses is an extremely rare and aggressive neoplasm. Despite aggressive management, the tumor carries a poor prognosis, with a high risk of local recurrence or distant metastases. The management strategy is based on that for pulmonary small cell cancer and includes platinum-based chemotherapy combined with radiotherapy. We are reporting a case of an 89-year-old female patient diagnosed with small cell carcinoma of right-sided ethmoid and sphenoid sinuses. The tumor was found to have invaded the right orbit and anterior cranial fossa. Metastases to cervical lymph nodes and bone were also found. Due to the extended stage and poor prognosis of the patient, the management plan is palliative chemoradiotherapy.

引用

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