Hypersensitivity reaction to carbamazepine presenting with, angioimmunoblastic lymphadenopathy generalized dermatitis and bone marrow granulomas

被引:0
作者
AlRikabi, AC [1 ]
Daif, A [1 ]
AlSheikh, OA [1 ]
AlSohaibani, MO [1 ]
AlRashed, RS [1 ]
AlOmair, AO [1 ]
机构
[1] KING SAUD UNIV, KING KHALID UNIV HOSP, DEPT PATHOL & MED, RIYADH 11472, SAUDI ARABIA
关键词
angioimmunoblastic lymphadenopathy; carbamazepine;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 29-year-old Saudi woman was admitted to the medical unit at King Khalid University Hospital with a history of generalized erythematous and vesicular skin rash, lymphadenopathy and hepatosplenomegaly. She was a known epileptic receiving carbamazepine treatment for the last 2 years. The lymph node biopsy showed features of angioimmunoblastic lymphadenopathy. The bone marrow trephine biopsy revealed the presence of small non-casesting epitheloid granulomas and her skin showed features of exfoliative and vesicular dermatitis. The histological features are described and discussed in addition to a detailed review of the literature and a comparison with other reported cases is made.
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页码:461 / 465
页数:5
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