UTILIZATION OF L-QUEBRACHITOL IN NATURAL PRODUCT SYNTHESIS - TOTAL SYNTHESIS AND ABSOLUTE-CONFIGURATION OF (-)-OUDEMANSIN-X

被引：16
作者：
CHIDA, N
YAMADA, K
OGAWA, S
机构：
[1] Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Kohoku-ku, Yokohama 223
来源：
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 17期
关键词：
D O I：
10.1039/p19930001957
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The stereoselective conversion of the naturally occurring optically active cyclitol, L-quebrachitol 2, into antifungal beta-methoxyacrylate, oudemansin X 1 is described. This first total synthesis of 1 fully confirmed the proposed absolute configuration of the antibiotic and showed the importance of 2 as a versatile chiral starting material in natural product syntheses.
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页码：1957 / 1962
页数：6
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