PREOPERATIVE EVALUATION OF MEDICALLY INTRACTABLE PARTIAL SEIZURES USING I-123 IOMAZENIL SPECT

被引：0

作者：

VENZ, S ^{[1
]}

CORDES, M ^{[1
]}

STRAUB, HB ^{[1
]}

HIERHOLZER, J ^{[1
]}

SCHRODER, R ^{[1
]}

RICHTER, W ^{[1
]}

SCHMITZ, B ^{[1
]}

MEENCKE, H ^{[1
]}

FELIX, R ^{[1
]}

机构：

[1] FREE UNIV BERLIN,KLINIKUM RUDOLF VIRCHOW W,NEUROL KLIN & POLIKLIN,D-13353 BERLIN,GERMANY

来源：

NUKLEARMEDIZIN | 1994年 / 33卷 / 05期

关键词：

FOCAL EPILEPSY; I-123-LOMAZENIL; VIDO EEG MONITORING; SPECT; MRI; EPILEPSY SURGERY;

D O I：

暂无

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

SPECT with the benzodiazepine receptor antagonist I-123-Iomazenil was performed in 33 patients with intractable partial seizures for pre-operative evaluation. The results combined with MRI and 99mTc-HMPAO-SPECT findings were com-pared with the video-assisted EEG monitoring (''gold standard'') which localised the focus in 25 patients. 11 patients underwent surgical resection of the epileptogenic area and became seizure-free for a period up to 13 months. The Iomazenil SPECT had a significantly higher sensitivity compared to 99mTc-HMPAO in the visualization of an epileptogenic area and should be regularly used in the diagnostic of medically intractable partial seizures.

引用

页码：189 / 193

页数：5

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