MULTICOMPONENT ADSORPTION AND CHROMATOGRAPHY WITH UNEVEN SATURATION CAPACITIES

被引:33
作者
GU, TY [1 ]
TSAI, GJ [1 ]
TSAO, GT [1 ]
机构
[1] PURDUE UNIV,RENEWABLE RESOURCES ENGN,W LAFAYETTE,IN 47907
关键词
D O I
10.1002/aic.690370906
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
In chromatographic separations involving elutes with large differences in the molecular size, the adsorption saturation capacities of the elutes may differ because of the differences in the degree of size exclusion. With uneven saturation capacities, isotherm crossovers may occur, which often results in selectivity reversal. In this work, a new multicomponent isotherm has been developed for this kind of system. The isotherm is an extension of the common multicomponent Langmuir isotherm and introduces no or a very limited number of new parameters for its construction. The isotherm crossover conditions have also been derived. Simulations based on a general rate model using the new isotherm have successfully demonstrated the phenomena of peak reversal and crossover of breakthrough curves.
引用
收藏
页码:1333 / 1340
页数:8
相关论文
共 20 条
[1]   OPERATIONAL MODES OF CHROMATOGRAPHIC-SEPARATION PROCESSES [J].
ANTIA, FD ;
HORVATH, C .
BERICHTE DER BUNSEN-GESELLSCHAFT-PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 1989, 93 (09) :961-968
[2]   ANALYTICAL AFFINITY-CHROMATOGRAPHY .1. LOCAL EQUILIBRIUM-THEORY AND THE MEASUREMENT OF ASSOCIATION AND INHIBITION CONSTANTS [J].
ARNOLD, FH ;
SCHOFIELD, SA ;
BLANCH, HW .
JOURNAL OF CHROMATOGRAPHY, 1986, 355 (01) :1-12
[3]   ANALYSIS OF AFFINITY SEPARATIONS .1. PREDICTING THE PERFORMANCE OF AFFINITY ADSORBERS [J].
ARNOLD, FH ;
BLANCH, HW ;
WILKE, CR .
CHEMICAL ENGINEERING JOURNAL AND THE BIOCHEMICAL ENGINEERING JOURNAL, 1985, 30 (02) :B9-B23
[4]   ANALYTICAL AFFINITY-CHROMATOGRAPHY .2. RATE THEORY AND THE MEASUREMENT OF BIOLOGICAL BINDING-KINETICS [J].
ARNOLD, FH ;
BLANCH, HW .
JOURNAL OF CHROMATOGRAPHY, 1986, 355 (01) :13-27
[5]   THE MODELING AND ANALYSIS OF THE ELUTION STAGE OF BIOSPECIFIC ADSORPTION IN FIXED-BEDS [J].
ARVE, BH ;
LIAPIS, AI .
BIOTECHNOLOGY AND BIOENGINEERING, 1987, 30 (05) :638-649
[6]   INTERACTION OF PROTEINS WITH IMMOBILIZED CU2+ - QUANTITATION OF ADSORPTION CAPACITY, ADSORPTION-ISOTHERMS AND EQUILIBRIUM-CONSTANTS BY FRONTAL ANALYSIS [J].
BELEW, M ;
YIP, TT ;
ANDERSSON, L ;
PORATH, J .
JOURNAL OF CHROMATOGRAPHY, 1987, 403 :197-206
[7]   PREDICTION OF THE PERFORMANCE OF PREPARATIVE AFFINITY-CHROMATOGRAPHY [J].
CHASE, HA .
JOURNAL OF CHROMATOGRAPHY, 1984, 297 (AUG) :179-202
[8]  
CHASE HA, 1984, CHEM ENG SCI, V39, P1099
[9]  
FALLAH MZ, 1990, J CHROMATOGR, V511, P1
[10]  
FROMENT GF, 1979, CHEM REACTOR ANAL DE, V529, P530