NONCLASSICAL ANTIMETABOLITES .25. INHIBITORS OF THYMIDINE KINASE .I. A NEW SPECTROPHOTOMETRIC ASSAY . INHIBITION BY NUCLEOSIDE DERIVATIVES

被引：53

作者：

BAKER, BR

SCHWAN, TJ

SANTI, DV

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1966年 / 9卷 / 01期

关键词：

D O I：

10.1021/jm00319a018

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：66 / &

共 34 条

[1]

BAKER BERNARD R., 1959, CANCER CHEMOTHERAPY REPTS, V4, P1

[2] ANALOGS OF TETRAHYDROFOLIC ACID .10. SYNTHETIC + ENZYMIC STUDIES ON CONTRIBUTION OF P-AMINOBENZOYL-L-GLUTAMATE MOIETY OF PYRIMIDYL ANALOGS TO BINDING TO SOME FOLIC COFACTOR AREA ENZYMES [J].

BAKER, BR ;

SANTI, DV ;

ALMAULA, PI ;

WERKHEISER, WC .

JOURNAL OF MEDICINAL CHEMISTRY, 1964, 7 (01) :24-&

[3] NONCLASSICAL ANTIMETABOLITES .18. SIMULATION OF 5'-PHOSPHORIBOSYL BINDING .2. OMEGA-URACIL ALKANOIC ACIDS RELATED TO 2'-DEOXYURIDYLATE [J].

BAKER, BR ;

CHHEDA, GB .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1965, 54 (01) :25-&

[4] FACTORS IN DESIGN OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS [J].

BAKER, BR .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1964, 53 (04) :347-&

[5] ANALOGS OF TETRAHYDROFOLIC ACID .27. HYDROPHOBIC BONDING TO DIHYDROFOLIC REDUCTASE BY 2-AMINO-4,6-DISUBSTITUTED-5-ALKYLPYRIMIDINES AND 1-ALKYL-4,6-DIAMINO-1,2-DIHYDRO-S-TRIAZINES [J].

BAKER, BR ;

HO, BT ;

SANTI, DV .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1965, 54 (10) :1415-&

[6] ANALOGS OF TETRAHYDROFOLIC ACID .26. SYNTHESIS OF SOME 5-ARYL AND 5-ARALKYL PYRIMIDINE-6-CARBOXYLIC ACIDS AND THEIR EFFECT ON DIHYDROFOLIC REDUCTASE AND THYMIDYLATE SYNTHETASE [J].

BAKER, BR ;

JORDAAN, JH .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1965, 2 (02) :162-&

[7] ANALOGS OF TETRAHYDROFOLIC ACID .9. SYNTHESIS OF N-[1-(2-AMINO-4-HYDROXY-6-PHENYL-5-PYRIMIDYL)-3-PROPYL]-P-AMINOBENZOYL-L-GLUTAMIC ACID, A NONCLASSICAL INHIBITOR OF SOME FOLIC COFACTOR AREA ENZYMES [J].

BAKER, BR ;

SHAPIRO, HS .

JOURNAL OF MEDICINAL CHEMISTRY, 1963, 6 (06) :664-&

[8] NONCLASSICAL ANTIMETABOLITES .19. SIMULATION OF 5'-PHOSPHORIBOSYL BINDING .3. RELATIVE CONTRIBUTION OF PHOSPHATE AND OTHER OXYGEN-CONTAINING FUNCTIONS TO BINDING OF 5'-PHOSPHORIBOSYL MOIETY TO SUCCINOADENYLATE KINOSYNTHETASE [J].

BAKER, BR ;

TANNA, PM .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1965, 54 (06) :845-&

[9] ANALOGS OF TETRAHYDROFOLIC ACID .22. EFFECTS OF MODIFICATION OF BRIDGE BETWEEN PYRIMIDYL AND PHENYL MOIETIES OF 2-AMINO-5-(3-ANILINOPROPYL)-6-METHYL-4-PYRIMIDINOL ON INHIBITION OF DIHYDROFOLIC REDUCTASE AND THYMIDYLATE SYNTHETASE 3 [J].

BAKER, BR ;

COWARD, JK .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1965, 54 (05) :714-&

[10] POTENTIAL ANTICANCER AGENTS .50. NON-CLASSICAL ANTIMETABOLITES .2. SOME FACTORS IN THE DESIGN OF EXO-ALKYLATING ENZYME INHIBITORS, PARTICULARLY OF LACTIC DEHYDROGENASE [J].

BAKER, BR ;

LEE, WW ;

SKINNER, WA ;

MARTINEZ, AP ;

TONG, E .

JOURNAL OF MEDICINAL & PHARMACEUTICAL CHEMISTRY, 1960, 2 (06) :633-657

← 1 2 3 4 →