SMALL-BOWEL OBSTRUCTION SECONDARY TO ACTIVATED-CHARCOAL AND ADHESIONS

被引:26
作者
GOULBOURNE, KB [1 ]
CISEK, JE [1 ]
机构
[1] WAYNE STATE UNIV,DETROIT RECEIVING HOSP UHC,DEPT EMERGENCY MED,4201 ST ANTOINE,DETROIT,MI 48201
关键词
D O I
10.1016/S0196-0644(94)70170-9
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Gastrointestinal obstruction is a rare complication of multiple-dose administration of activated charcoal. Previous reports deal only with obstruction after ingestion of drugs that impair gastrointestinal motility. This patient developed a small-bowel obstruction associated with the administration of multiple doses of activated charcoal (350 g, total) for treatment of theophylline toxicity. This patient also had low-grade, previously asymptomatic adhesions at the ileocecal valve. A 4.5 x 5 x 3-cm aggregate of charcoal was surgically removed from the distal ileum.
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页码:108 / 110
页数:3
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  • [1] Berlinger WG, Spector R, Goldberg MJ, Et al., Enhancement of theophylline clearance by oral activated charcoal, Clin Pharmacol Ther, 33, pp. 351-354, (1983)
  • [2] Mahutte CK, True RJ, Michiels TM, Et al., Increased serum theophylline clearance with orally administered activated charcoal, Am Rev Respir Dis, 128, pp. 820-822, (1983)
  • [3] Gal P, Miller A, McCur JD, Oral activated charcoal to enhance theophylline elimination in an acute overdose, JAMA, 251, pp. 3130-3131, (1984)
  • [4] Sintek C, Hendeles L, Weinberger M, Inhibition of theophylline absorption by activated charcoal, J Pediatr, 94, pp. 314-316, (1979)
  • [5] Park GD, Radomski L, Goldberg MJ, Et al., Effects of size and frequency of oral doses of charcoal on theophylline clearance, Clin Pharmacol Ther, 34, pp. 663-666, (1983)
  • [6] Kulig KW, Bar-Or D, Rumack BH, Et al., Intravenous theophylline poisoning and multiple-dose charcoal in an animal model, Ann Emerg Med, 16, pp. 842-846, (1987)
  • [7] Lim DT, Singh P, Nourtsis S, Et al., Absorption inhibition and enhancement of elimination of sustained-release theophylline tablets by oral activated charcoal, Ann Emerg Med, 15, pp. 1303-1307, (1986)
  • [8] Tenenbein M, Multiple doses of activated charcoal: Time for reappraisal?, Ann Emerg Med, 20, pp. 529-530, (1991)
  • [9] Neuvonen PJ, Olkkola KT, Oral activated charcoal in the treatment of intoxications: Role of single and repeated doses, Med Toxicol, 3, pp. 33-58, (1988)
  • [10] Bauer H, Constipating effect of charcoal, Arch Exp Pathol Pharmacol, 134, (1928)