MOLECULAR-CLONING AND SEQUENCE-ANALYSIS OF THE GENE OF THE MOLYBDENUM-CONTAINING ALDEHYDE OXIDOREDUCTASE OF DESULFOVIBRIO-GIGAS - THE DEDUCED AMINO-ACID-SEQUENCE SHOWS SIMILARITY TO XANTHINE DEHYDROGENASE

被引：50
作者：
THOENES, U
FLORES, OL
NEVES, A
DEVREESE, B
VANBEEUMEN, JJ
HUBER, R
ROMAO, MJ
LEGALL, J
MOURA, JJG
RODRIGUESPOUSADA, C
机构：
[1] GULBENKIAN INST SCI,GENET MOLEC LAB,OEIRAS,PORTUGAL
[2] VAKGRP BIOCHEM FYSIOL & MICROBIOL,GHENT,BELGIUM
[3] INST SUPER TECN,DEPT QUIM,LISBON,PORTUGAL
[4] INST TECNOL QUIM & BIOL,OEIRAS,PORTUGAL
[5] UNIV NOVA LISBOA,FCT,DEPT QUIM,MONTE DE CAPARICA,PORTUGAL
[6] UNIV GEORGIA,DEPT BIOCHEM,ATHENS,GA
来源：
EUROPEAN JOURNAL OF BIOCHEMISTRY | 1994年 / 220卷 / 03期
关键词：
D O I：
10.1111/j.1432-1033.1994.tb18693.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this report, we describe the isolation of a 4020-bp genomic PstI fragment of Desulfovibrio gigas harboring the aldehyde oxido-reductase gene. The aldehyde oxido-reductase gene spans 2718 bp of genomic DNA and codes for a protein with 906 residues. The protein sequence shows an average 52% (+/- 1.5%) similarity to xanthine dehydrogenase from different organisms. The codon usage of the aldehyde oxidoreductase is almost identical to a calculated codon usage of the Desulfovibrio bacteria.
引用
收藏
页码：901 / 910
页数：10
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