THE ACTION OF DIETHYLAMINOSULFUR TRIFLUORIDE (DAST) ON TRANS-4-AMIDO-3-CHROMANOLS - PREPARATION OF CIS-AMIDOALCOHOLS VIA OXAZOLINES

被引：72

作者：

BURRELL, G ^{[1
]}

EVANS, JM ^{[1
]}

JONES, GE ^{[1
]}

STEMP, G ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,MED RES CTR,THE PINNACLES,HARLOW CM19 5AD,ESSEX,ENGLAND

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(00)94467-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of a variety of trans-4-amido-3-chromanols (3) with DAST gives oxazolines (4) which can be hydrolysed to give the corresponding cis-amido-alcohols (5). Similar treatment of the trans-4-ureido-3-chromanol (8) gave the unexpected 4-fluoro-3-ureidochromanol (9) as the major product. © 1990.

引用

页码：3649 / 3652

页数：4

共 4 条

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