STRUCTURE OF A 6-TETRAHYDROXYBUTYL-SUBSTITUTED 5,6,7,8-TETRAHYDROPTERIDINE

被引：9
作者：
BEDDOES, RL
RUSSELL, JR
GARNER, CD
JOULE, JA
机构：
来源：
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 1993年 / 49卷
关键词：
D O I：
10.1107/S0108270193001593
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The crystal structure of 2-acetamido-5-benzyloxy-carbonyl-3,4,5,6,7,8-hexahydro-4-oxo-6-(D-arabino-tetrahydroxybutyl)pteridine tetraacetate. (5), shows that reduction of 2-acetamido-3,4-dihydro-4-oxo-6-(D-arabino-tetrahydroxybutyl)pteridine tetraacetate, (4), with sodium cyanoborohydride in the presence of benzyl chloroformate achieves saturation of the pyrazine ring with regioselective protection at nitrogen N(5).
引用
收藏
页码：1649 / 1652
页数：4
相关论文
共 16 条
[1]   STRUCTURE OF A 6-(TETRAHYDROXYBUTYL)-SUBSTITUTED PTERIDINE [J].
BEDDOES, RL ;
RUSSELL, JR ;
GARNER, CD ;
JOULE, JA .
ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 1993, 49 :413-416
[2]  
Cromer D.T, 1974, INT TABLES XRAY CRYS, VIV
[3]  
GARDLIK S, 1990, J BIOL CHEM, V265, P13047
[4]   DISPERSION CORRECTIONS + CRYSTAL STRUCTURE REFINEMENTS [J].
IBERS, JA ;
HAMILTON, WC .
ACTA CRYSTALLOGRAPHICA, 1964, 17 (06) :781-&
[5]  
Johnson J. L., 1980, MOLYBDENUM MOLYBDENU, P345
[6]   MODEL STUDIES RELATED TO THE COFACTOR OF OXOMOLYBDOENZYMES .2. QUINOXALIN-2-YL-ETHANE AND ETHENE-1,2-DITHIOLS [J].
LARSEN, L ;
GARNER, CD ;
JOULE, JA .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1989, (12) :2311-2316
[7]   MODEL STUDIES RELATED TO THE COFACTOR OF OXOMOLYBDOENZYMES .3. [J].
LARSEN, L ;
ROWE, DJ ;
GARNER, CD ;
JOULE, JA .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1989, (12) :2317-2327
[8]  
MOTHERWELL WDS, 1978, PLUTO PROGRAM PLOTTI
[9]  
Pope M.T., 1983, HETEROPOLY ISOPOLY O
[10]  
RAJAGOPALAN KV, 1991, ADV ENZYMOL RAMB, V64, P215
12