CHEMOENZYMATIC SYNTHESIS OF BOTH ENANTIOMERS OF FLUOXETINE

被引:31
作者
CHENEVERT, R
FORTIER, G
机构
关键词
D O I
10.1246/cl.1991.1603
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Both enantiomers of fluoxetine have been synthesized from ethyl benzoylacetate. The key step is the enantioselective reduction of the starting material by baker's yeast.
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页码:1603 / 1606
页数:4
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