SYNTHESIS AND ANTIVIRAL ACTIVITY OF VARIOUS ESTERS OF 9-[(1,3-DIHYDROXY-2-PROPOXY)METHYL]GUANINE

被引：30

作者：

MARTIN, JC ^{[1
]}

TIPPIE, MA ^{[1
]}

MCGEE, DPC ^{[1
]}

VERHEYDEN, JPH ^{[1
]}

机构：

[1] SYNTEX RES CORP, INST BIOORGAN CHEM, PALO ALTO, CA 94304 USA

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1987年 / 76卷 / 02期

关键词：

D O I：

10.1002/jps.2600760221

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：180 / 184

页数：5

共 15 条

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[2] PRODRUGS OF 9-(BETA-D-ARABINOFURANOSYL)ADENINE .2. SYNTHESIS AND EVALUATION OF A NUMBER OF 2',3'-DI-O-ACYL DERIVATIVES AND 3',5'-DI-O-ACYL DERIVATIVES
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[3] PRODRUGS OF 9-BETA-D-ARABINOFURANOSYLADENINE .1. SYNTHESIS AND EVALUATION OF SOME 5'-(O-ACYL) DERIVATIVES
BAKER, DC
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (12) : 1218 - 1221
[4] BENJAMIN EJ, UNPUB PARTITION COEF
[5] CHAPLIN M, UNPUB
[6] UNIQUE SPECTRUM OF ACTIVITY OF 9-[(1,3-DIHYDROXY-2-PROPOXY)METHYL]-GUANINE AGAINST HERPESVIRUSES INVITRO AND ITS MODE OF ACTION AGAINST HERPES-SIMPLEX VIRUS TYPE-1
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LIN, JC
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (09): : 2767 - 2770
[7] FINNEY D J, 1971, P333
[8] ACTIVITY OF 9-(1,3-DIHYDROXY-2-PROPOXYMETHYL)GUANINE COMPARED WITH THAT OF ACYCLOVIR AGAINST HUMAN, MONKEY, AND RODENT CYTOMEGALOVIRUSES
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MATTHEWS, TR
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1985, 28 (02) : 240 - 245
[9] KORETZ SH, 1986, NEW ENGL J MED, V314, P801, DOI 10.1056/NEJM198603273141301
[10] 9-[(1,3-DIHYDROXY-2-PROPOXY)METHYL]GUANINE - A NEW POTENT AND SELECTIVE ANTIHERPES AGENT
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MATTHEWS, TR
VERHEYDEN, JPH
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (05) : 759 - 761

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