Fatal Metastatic Cutaneous Squamous Cell Carcinoma Evolving from a Localized Verrucous Epidermal Nevus

被引:7
作者
Riad, Hassan [1 ]
Mansour, Khaled [1 ]
Al Sada, Hussein [1 ]
Al Naama, Khalifa [1 ]
Al Shaigy, Amal [1 ]
Hussain, Khairunnisa [1 ]
机构
[1] Rumailah Hosp, POB 3050, Doha, Qatar
来源
CASE REPORTS IN DERMATOLOGY | 2013年 / 5卷 / 03期
关键词
Fatal metastatic cutaneous squamous cell carcinoma; Localized verrucous epidermal nevus; Cutaneous squamous cell carcinoma; Epidermal nevus; Metastasis;
D O I
10.1159/000355605
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
A malignant transformation is known to occur in many nevi such as a sebaceous nevus or a basal cell nevus, but a verrucous epidermal nevus has only rarely been associated with neoplastic changes. Keratoacanthoma, multifocal papillary apocrine adenoma, multiple malignant eccrine poroma, basal cell carcinoma and cutaneous squamous cell carcinoma (CSCC) have all been reported to develop from a verrucous epidermal nevus. CSCC has also been reported to arise from other nevoid lesions like a nevus comedonicus, porokeratosis, a sebaceous nevus, an oral sponge nevus and an ichthyosiform nevus with CHILD syndrome. Here we report a case of progressive poorly differentiated CSCC arising from a localized verrucous epidermal nevus, which caused both spinal cord and brain metastasis. (C) 2013 S. Karger AG, Basel
引用
收藏
页码:272 / 282
页数:11
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