IMMUNOINTERVENTION IN TYPE-1 (INSULIN-DEPENDENT) DIABETES-MELLITUS

被引：5

作者：

KEYMEULEN, B ^{[1
]}

SOMERS, G ^{[1
]}

机构：

[1] VUB,AZ,DEPT INTERNE GENEESKUNDE,LAARBEEKLAAN 101,B-1090 BRUSSELS,BELGIUM

来源：

ACTA CLINICA BELGICA | 1993年 / 48卷 / 02期

关键词：

D O I：

10.1080/17843286.1993.11718292

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The hitherto identified hallmarks of the autoimmune aspects in Type 1 diabetes are reviewed. Their implication in the disclosure of the pre-clinical phase of the disease is put forward. The possible delineation of this pre-diabetic phase can lead to an early immunotherapeutic approach. The effect of immunomodulation by agents such as azathioprine, cyclosporin A and nicotinamide in newly diagnosed diabetes and the use of some of these drugs in clinical trials on pre-diabetic individuals are discussed.

引用

页码：86 / 95

页数：10