BIOLOGICAL-ACTIVITY OF RECOMBINANT HUMAN INTERLEUKIN-2 PRODUCED IN ESCHERICHIA-COLI

被引:770
作者
ROSENBERG, SA [1 ]
GRIMM, EA [1 ]
MCGROGAN, M [1 ]
DOYLE, M [1 ]
KAWASAKI, E [1 ]
KOTHS, K [1 ]
MARK, DF [1 ]
机构
[1] CETUS CORP, EMERYVILLE, CA 94608 USA
关键词
D O I
10.1126/science.6367046
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:1412 / 1414
页数:3
相关论文
共 33 条
[2]  
BAKER PE, 1978, J IMMUNOL, V121, P2168
[3]   INHIBITION OF INTRACTABLE NUCLEASES WITH RIBONUCLEOSIDE-VANADYL COMPLEXES - ISOLATION OF MESSENGER RIBONUCLEIC-ACID FROM RESTING LYMPHOCYTES [J].
BERGER, SL ;
BIRKENMEIER, CS .
BIOCHEMISTRY, 1979, 18 (23) :5143-5149
[4]   AUGMENTATION OF THE ANTI-TUMOR THERAPEUTIC EFFICACY OF LONG-TERM CULTURED LYMPHOCYTES-T BY INVIVO ADMINISTRATION OF PURIFIED INTERLEUKIN-2 [J].
CHEEVER, MA ;
GREENBERG, PD ;
FEFER, A ;
GILLIS, S .
JOURNAL OF EXPERIMENTAL MEDICINE, 1982, 155 (04) :968-980
[5]   AN IMPROVED PROCEDURE FOR UTILIZING TERMINAL TRANSFERASE TO ADD HOMOPOLYMERS TO THE 3' TERMINI OF DNA [J].
DENG, G ;
WU, R .
NUCLEIC ACIDS RESEARCH, 1981, 9 (16) :4173-4188
[6]   MOLECULAR-CLONING OF HUMAN INTERLEUKIN-2 CARRIER DNA AND ITS EXPRESSION IN ESCHERICHIA-COLI [J].
DEVOS, R ;
PLAETINCK, G ;
CHEROUTRE, H ;
SIMONS, G ;
DEGRAVE, W ;
TAVERNIER, J ;
REMAUT, E ;
FIERS, W .
NUCLEIC ACIDS RESEARCH, 1983, 11 (13) :4307-4323
[7]  
DONOHUE JH, 1983, J IMMUNOL, V130, P2203
[8]   BIOCHEMICAL AND BIOLOGICAL CHARACTERIZATION OF LYMPHOCYTE REGULATORY MOLECULES .5. IDENTIFICATION OF AN INTERLEUKIN 2-PRODUCING HUMAN-LEUKEMIA T-CELL LINE [J].
GILLIS, S ;
WATSON, J .
JOURNAL OF EXPERIMENTAL MEDICINE, 1980, 152 (06) :1709-1719
[9]  
GILLIS S, 1979, J EXP MED, V149, P1460, DOI 10.1084/jem.149.6.1460
[10]   SYNTHESIS OF HUMAN FIBROBLAST INTERFERON BY ESCHERICHIA-COLI [J].
GOEDDEL, DV ;
SHEPARD, HM ;
YELVERTON, E ;
LEUNG, D ;
CREA, R ;
SLOMA, A ;
PESTKA, S .
NUCLEIC ACIDS RESEARCH, 1980, 8 (18) :4057-4074