STUDIES ON ANTIVIRAL AGENTS .1. ANTIVIRAL ACTIVITY OF PYRIDOBENZOAZOLES

被引：11
作者：
SHIGETA, S [1 ]
HOSOYA, M [1 ]
MOCHIZUKI, S [1 ]
CHIBA, T [1 ]
机构：
[1] TOHOKU UNIV, INST PHARMACEUT, SENDAI, MIYAGI 980, JAPAN
来源：
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN | 1988年 / 108卷 / 09期
关键词：
D O I：
10.1248/yakushi1947.108.9_856
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Various pyridoazoles have been synthesized and tested against respiratory syncytical virus, Flu-V (A-Ishikawa/17/82), and herpes simplex virus (KOS-1). Among these compounds, 2-carboxy-4-ethoxycarbonyl-1-oxo-1H,5H-pyrido[1,2-a]benzimidazole (2) and 2-benzamido-4-cyano-1-oxo-1H,5H-pyrido[1,2-a]benzimidazole (4) were found to have significant antiviral activity.
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收藏
页码：856 / 859
页数：4
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