NEUROTRANSMITTER TRANSPORTERS (PLUS) - A PROMISING NEW GENE FAMILY

被引：167
作者：
UHL, GR
机构：
[1] JOHNS HOPKINS UNIV, SCH MED, DEPT NEUROL, BALTIMORE, MD 21224 USA
[2] JOHNS HOPKINS UNIV, SCH MED, DEPT NEUROSCI, BALTIMORE, MD 21224 USA
来源：
TRENDS IN NEUROSCIENCES | 1992年 / 15卷 / 07期
关键词：
D O I：
10.1016/0166-2236(92)90068-J
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Neurotransmitter transporter genes encode proteins with 12 putative transmembrane regions, which mediate Na+-dependent reaccumulation of released neurotransmitters into presynaptic terminals and are the sites of action of important abused and therapeutic drugs. Studies of these genes show promise for improving our understanding of transport mechanisms and modes of drug action, and may even uncover previously unanticipated neurotransmitters.
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收藏
页码：265 / 268
页数：4
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