The voices of donor offspring and their families are missing from the debate regarding gamete donor anonymity v. openness in Israel, their unique predicament unheeded. Despite a context of worldwide change, various fears and myths impede the outlawing of donor anonymity, with Israel's medical establishment and legal representatives invested in maintaining a status quo characterized by regulations that discriminate between families whose members know their biological parents/siblings and those who do not. The most prominent of these is that abolishing anonymity leads to long-term shortage of donors, despite well-documented evidence to the contrary. A review of key research findings regarding the particular needs and experiences of offspring, recipients and donors clearly supports the need for a well thought-out re-evaluation of persistent fears and myths via the prism of grassroots reality. This evidence-based approach can lead to the formulation of recommendations that should facilitate, reflect and constitute such policy change.