ENZYMATIC ESTERIFICATION AND DE-ESTERIFICATION OF CARBOHYDRATES - SYNTHESIS OF A NATURALLY-OCCURRING RHAMNOPYRANOSIDE OF P-HYDROXYBENZALDEHYDE AND A SYSTEMATIC INVESTIGATION OF LIPASE-CATALYZED ACYLATION OF SELECTED ARYLPYRANOSIDES

被引：51

作者：

BASHIR, NB ^{[1
]}

PHYTHIAN, SJ ^{[1
]}

REASON, AJ ^{[1
]}

ROBERTS, SM ^{[1
]}

机构：

[1] WELLCOME FDN LTD,DARTFORD DA1 5AH,KENT,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1995年 / 18期

关键词：

D O I：

10.1039/p19950002203

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regiocontrolled esterification and de-esterification of mono- and di-saccharides is reviewed. New results involving the enzyme-catalysed regioselective acylation of ribo-110, arabino-112, 119, xylo-111, and rhamnopyranosides 116, 118 (as well as two arylpyranosides 125 and 136), are reported. This methodology is then applied to the total synthesis of the naturally occurring rhamnopyranoside 4-(4-O-acetyl-alpha-L-rhamnosyloxy)benzaldehyde 122.

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页码：2203 / 2222

页数：20

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