CHANGES IN BODY-TEMPERATURE MARKEDLY AFFECT STRIATAL DOPAMINE RELEASE AND METABOLISM - AN INVIVO STUDY

被引：12
|
作者：
BRANNAN, T [1 ]
MARTINEZTICA, J [1 ]
YAHR, MD [1 ]
机构：
[1] CUNY MT SINAI SCH MED,DEPT NEUROL,NEW YORK,NY 10029
来源：
JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION | 1992年 / 89卷 / 03期
关键词：
DOPAMINE; BODY TEMPERATURE; PARKINSONS DISEASE; CEREBRAL MICRODIALYSIS;
D O I：
10.1007/BF01250671
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Dopamine release and metabolism in the corpus striatum increased markedly when the core body temperature of anesthetized rats was increased from 35-degrees to 41-degrees-C while temperatures below 34-degrees were associated with a marked attenuation of dopamine release. These observations may have clinical relevance in cases where alterations in body temperature are associated with extrapyramidal dysfunction.
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页码：193 / 196
页数：4
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