HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF THE ENANTIOMERS AND DIASTEREOMERS OF PRIMAQUINE AND ITS METABOLITES

被引：8
作者：
BAKER, JK [1 ]
CLARK, AM [1 ]
HUFFORD, CD [1 ]
机构：
[1] UNIV MISSISSIPPI,SCH PHARM,DEPT PHARMACOGNOSY,UNIVERSITY,MS 38677
来源：
JOURNAL OF LIQUID CHROMATOGRAPHY | 1986年 / 9卷 / 2-3期
关键词：
D O I：
10.1080/01483918608076649
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：493 / 509
页数：17
相关论文
共 11 条
[1]   HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF THE METABOLISM OF PRIMAQUINE AND THE IDENTIFICATION OF A NEW MAMMALIAN METABOLITE [J].
BAKER, JK ;
MCCHESNEY, JD ;
HUFFORD, CD ;
CLARK, AM .
JOURNAL OF CHROMATOGRAPHY, 1982, 230 (01) :69-77
[2]   METABOLISM AND DISTRIBUTION OF PRIMAQUINE IN MONKEYS [J].
BAKER, JK ;
BEDFORD, JA ;
CLARK, AM ;
MCCHESNEY, JD .
PHARMACEUTICAL RESEARCH, 1984, (02) :98-100
[3]  
CLARK AM, 1984, APPL ENVIRON MICROB, V47, P537, DOI 10.1128/AEM.47.3.537-539.1984
[4]   PRIMAQUINE - METABOLISM BY MICROORGANISMS AND C-13-NUCLEAR MAGNETIC-RESONANCE ASSIGNMENTS [J].
CLARK, AM ;
HUFFORD, CD ;
MCCHESNEY, JD .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1981, 19 (02) :337-341
[5]   PRODUCTION OF A NOVEL DIMERIC METABOLITE OF PRIMAQUINE BY STREPTOMYCES-RIMOSUS [J].
CLARK, AM ;
HUFFORD, CD ;
PURI, RK ;
MCCHESNEY, JD .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1984, 47 (03) :540-543
[6]   MICROBIAL-METABOLISM STUDIES ON THE MAJOR MICROBIAL AND MAMMALIAN METABOLITE OF PRIMAQUINE [J].
HUFFORD, CD ;
CLARK, AM ;
QUINONES, IN ;
BAKER, JK ;
MCCHESNEY, JD .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1983, 72 (01) :92-94
[7]   STEREOCHEMISTRY OF DIMERIC MICROBIAL METABOLITES OF PRIMAQUINE [J].
HUFFORD, CD ;
CLARK, AM ;
MCCHESNEY, JD ;
BAKER, JK .
JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (15) :2822-2823
[8]  
HUFFORD CD, 1984, UNPUB J ORG CHEM
[9]   PHARMACOKINETICS OF PRIMAQUINE IN MAN - IDENTIFICATION OF THE CARBOXYLIC-ACID DERIVATIVE AS A MAJOR PLASMA METABOLITE [J].
MIHALY, GW ;
WARD, SA ;
EDWARDS, G ;
LEORME, M ;
BRECKENRIDGE, AM .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 17 (04) :441-446
[10]   COMPARISON OF CURATIVE ANTIMALARIAL ACTIVITIES AND TOXICITIES OF PRIMAQUINE AND ITS D AND L ISOMERS [J].
SCHMIDT, LH ;
ALEXANDER, S ;
ALLEN, L ;
RASCO, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1977, 12 (01) :51-60
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