SYNTHESIS OF 4-HYDROXY-3-TRIFLUOROMETHYLPYRAZOLES

被引：12

作者：

IWATA, S

NAMEKATA, J

TANAKA, K

MITSUHASHI, K

机构：

[1] Faculty of Engineering, Seikei University, Tokyo, 180, Musashino-shi

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1991年 / 28卷 / 08期

关键词：

D O I：

10.1002/jhet.5570280830

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Trifluoroacetaldehyde hydrazones are condensed with glyoxals to give 4-hydroxy-3-trifluoromethylpyrazoles, the reaction offering a novel route to 4-hydroxypyrazoles carrying trifluoromethyl group. The 4-hydroxyl group was easily converted to its derivatives by the reaction with various electrophiles.

引用

页码：1971 / 1976

页数：6

共 5 条

[1] REACTIONS OF GLYOXALS WITH HYDRAZONES - A NEW ROUTE TO 4-HYDROXYPYRAZOLES [J].