SPIRONOLACTONE AND CYTOCHROME-P-450 - IMPAIRMENT OF STEROID 21-HYDROXYLATION IN ADRENAL-CORTEX

被引：61

作者：

MENARD, RH

BARTTER, FC

GILLETTE, JR

机构：

[1] RHODE ISLAND HOSP,PROVIDENCE,RI 02902

[2] BROWN UNIV,DIV BIOL & MED SCI,PROVIDENCE,RI 02902

[3] NHLI,BETHESDA,MD 20014

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1976年 / 173卷 / 02期

关键词：

D O I：

10.1016/0003-9861(76)90277-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：395 / 402

页数：8

共 9 条

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[3]

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[4] SPIRONOLACTONE AND CYTOCHROME-P-450 - IMPAIRMENT OF STEROID HYDROXYLATION IN ADRENAL-CORTEX [J].

MENARD, RH ;

MARTIN, HF ;

STRIPP, B ;

GILLETTE, JR ;

BARTTER, FC .

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[5] SPIRONOLACTONE AND TESTICULAR CYTOCHROME-P-450 - DECREASED TESTOSTERONE FORMATION IN SEVERAL SPECIES AND CHANGES IN HEPATIC DRUG-METABOLISM [J].

MENARD, RH ;

STRIPP, B ;

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ENDOCRINOLOGY, 1974, 94 (06) :1628-1636

[6] STUDIES OF CYTOCHROME-P-450 IN TESTIS MICROSOMES [J].

MENARD, RH ;

PURVIS, JL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1973, 154 (01) :8-18

[7]

MENARD RH, 1974, 56TH ANN M END SOC, pA104

[8]

OMURA T, 1964, J BIOL CHEM, V239, P2370

[9] EFFECT OF SPIRONOLACTONE ON SEX-HORMONES IN MAN [J].

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TAYLOR, AA ;

BARTTER, FC ;

GILLETTE, JR ;

LORIAUX, DL ;

EASLEY, R ;

MENARD, RH .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1975, 41 (04) :777-781

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