Sarcoidosis: old certainties and new perspectives

被引：8

作者：

Tana, Claudio ^{[1
,2
]}

Tana, Marco ^{[1
]}

Mezzetti, Andrea ^{[1
]}

Schiavone, Cosima ^{[1
,2
]}

机构：

[1] Univ Gabriele Annunzio, Dipartimento Med & Sci Invecchiamento Osped Clini, Chieti, Italy

[2] Univ Gabriele Annunzio, UO Dipartimentale Ecog Internist Osped Clinicizza, Chieti, Italy

来源：

ITALIAN JOURNAL OF MEDICINE | 2012年 / 6卷 / 03期

关键词：

Sarcoidosis; HLA antigens; Granuloma; Peptidyl-dipeptidase A; Adalimumab;

D O I：

10.1016/j.itjm.2012.05.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: Sarcoidosis is the paradigm of the internistic disease. It virtually affects every organ and tissue and is characterized by the presence of noncaseating granulomas. A holistic view is needed for the diagnosis and treatment of the disease. The authors provide an overview on several recently published studies, which pose new perspectives on the approach to the disease. Materials and methods: The authors reviewed the scientific literature focusing on new etiopathogenetic, diagnostic and therapeutic data. Results and discussion: A multimodal approach is appropriate and effective in the diagnosis and treatment of systemic diseases such as sarcoidosis. In this context, the internist plays a key role more than any other specialist. (C) 2012 Elsevier Srl. All rights reserved.

引用

页码：186 / 194

页数：9

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