H-1-NMR ANALYSIS OF ISOMERIC 2'(3')-O-TRIALKYLSILYL AND 2'(3')-O-METHYL RIBONUCLEOSIDES

被引：0

作者：

MILECKI, J ^{[1
]}

POPENDA, M ^{[1
]}

ADAMIAK, RW ^{[1
]}

机构：

[1] POLISH ACAD SCI,INST BIOORGAN CHEM,PL-61704 POZNAN,POLAND

来源：

POLISH JOURNAL OF CHEMISTRY | 1994年 / 68卷 / 02期

关键词：

NMR; H-1; SI-29; 2'-O-TRIALKYLSILYL-; 2'-O-METHYL-RIBONUCLEOSIDES; 2'(3')-ISOMERS;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Resonances of ribose moieties of both 2'(3')-O-trialkylsilyl and 2'(3')-O-methyl isomers of 5'-O-dimethoxytrityl-N-protected ribonucleosides were assigned by H-1, H-1 COSY. The upfield shift of the H-2' or H-3' signal indicates the O-methylation site. The difference in chemical shifts of methyl protons of the 1-butyl-dimethylsilyl protective group allows assignment of the position of the O-trialkylsilyl substituent. For the latter the Si-29 NMR data are also presented.

引用

页码：275 / 280

页数：6

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