Colistin and tigecycline for management of external ventricular device-related ventriculitis due to multidrug-resistant Acinetobacter baumannii

被引:8
作者
Shrestha, Gentle Sunder [1 ]
Tamang, Sushil [1 ]
Paneru, Hem Raj [1 ]
Shrestha, Pramesh Sunder [1 ]
Keyal, Niraj [1 ]
Acharya, Subhash Prasad [1 ]
Marhatta, Moda Nath [1 ]
Shilpakar, Sushil [2 ]
机构
[1] Tribhuvan Univ, Teaching Hosp, Inst Med, Dept Anaesthesiol, Kathmandu, Nepal
[2] Tribhuvan Univ, Teaching Hosp, Dept Surg, Neurosurg Unit, Kathmandu, Nepal
关键词
Acinetobacter baumannii; colistin; intraventricular; multidrug resistant; tigecycline; ventriculitis;
D O I
10.4103/0976-3147.176194
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Acinetobacter baumannii is an important cause of nosocomial ventriculitis associated with external ventricular device (EVD). It is frequently multidrug resistant (MDR), carries a poor outcome, and is difficult to treat. We report a case of MDR Acinetobacter ventriculitis treated with intravenous and intraventricular colistin together with intravenous tigecycline. The patient developed nephrotoxicity and poor neurological outcome despite microbiological cure. Careful implementation of bundle of measures to minimize EVD-associated ventriculitis is valuable.
引用
收藏
页码:450 / 452
页数:3
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