THE FORMATION OF PEROXYNITRITE IN-VIVO FROM NITRIC-OXIDE AND SUPEROXIDE

被引：182

作者：

SQUADRITO, GL ^{[1
]}

PRYOR, WA ^{[1
]}

机构：

[1] LOUISIANA STATE UNIV,INST BIODYNAM,BATON ROUGE,LA 70803

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 1995年 / 96卷 / 02期

关键词：

NITRIC OXIDE; PEROXYNITRITE; SUPEROXIDE; REACTION; KINETICS; FREE RADICALS; ENDOTHELIUM;

D O I：

10.1016/0009-2797(94)03591-U

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Peroxynitrite is predicted to be formed in vivo from the reaction of nitric oxide and superoxide. Nitric oxide at concentrations as low as 3 nM is expected to compete efficiently for superoxide near the surface of endothelial cells, based on competition kinetics.

引用

页码：203 / 206

页数：4

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