A NEW TECHNIQUE TO STUDY THE MECHANICAL-PROPERTIES OF COLLAGEN LATTICES

被引：40

作者：

CHAPUIS, JF ^{[1
]}

AGACHE, P ^{[1
]}

机构：

[1] CHU ST JACQUES,CUTANEOUS BIOL LAB,F-25030 BESANCON,FRANCE

来源：

JOURNAL OF BIOMECHANICS | 1992年 / 25卷 / 01期

关键词：

D O I：

10.1016/0021-9290(92)90250-5

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A new technique to study the mechanical properties of collagen lattices or dermal equivalents is described. With the help of the load-extension curve obtained with a uniaxial traction apparatus, a stiffness modulus varying from 0.06 to 1 MPa is calculated from the studied parameters (duration of culture, collagen and fibroblast concentration). The technique is presented as a new tool for testing the effect of pharmacological agents on the mechanical properties of the skin.

引用

页码：115 / 120

页数：6

共 15 条

[1] MECHANICAL-PROPERTIES AND YOUNGS MODULUS OF HUMAN-SKIN INVIVO
AGACHE, PG
MONNEUR, C
LEVEQUE, JL
DERIGAL, J
[J]. ARCHIVES OF DERMATOLOGICAL RESEARCH, 1980, 269 (03) : 221 - 232
[2] PRODUCTION OF A TISSUE-LIKE STRUCTURE BY CONTRACTION OF COLLAGEN LATTICES BY HUMAN-FIBROBLASTS OF DIFFERENT PROLIFERATIVE POTENTIAL INVITRO
BELL, E
IVARSSON, B
MERRILL, C
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (03) : 1274 - 1278
[3] THE COLLAGEN LATTICE - A MODEL FOR STUDYING THE PHYSIOLOGY, BIOSYNTHETIC FUNCTION AND PHARMACOLOGY OF THE SKIN
COULOMB, B
DUBERTET, L
MERRILL, C
TOURAINE, R
BELL, E
[J]. BRITISH JOURNAL OF DERMATOLOGY, 1984, 111 : 83 - 87
[4] DALY CH, 1982, J INVEST DERMATOL, V79, P17
[5] DELVOYE P, 1986, J INVEST DERMATOL, V87, P135
[6] DELVOYE P, 1988, J INVEST DERMATOL, V91, P393
[7] GUIDRY C, 1986, COLLAGEN REL RES, V6, P515
[8] MEASUREMENTS OF THE ISOMETRIC CONTRACTILE FORCES GENERATED BY DOG PERIODONTAL-LIGAMENT FIBROBLASTS INVITRO
KASUGAI, S
SUZUKI, S
SHIBATA, S
YASUI, S
AMANO, H
OGURA, H
[J]. ARCHIVES OF ORAL BIOLOGY, 1990, 35 (08) : 597 - 601
[9] THE MEASUREMENT AND MODELING OF THE MECHANICAL-PROPERTIES OF HUMAN-SKIN INVIVO .2. THE MODEL
MANSCHOT, JFM
BRAKKEE, AJM
[J]. JOURNAL OF BIOMECHANICS, 1986, 19 (07) : 517 - 521
[10] PIERARD GE, 1984, THESIS LIEGE

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