MECHANISMS OF N-DEMETHYLATION REACTIONS CATALYZED BY CYTOCHROME-P-450 AND PEROXIDASES

被引：0

作者：

HOLLENBERG, PF

MIWA, GT

WALSH, JS

DWYER, LA

RICKERT, DE

KEDDERIS, GL

机构：

[1] NORTHWESTERN UNIV,SCH MED,DEPT MOLEC BIOL,CHICAGO,IL 60611

[2] CHEM IND INST TOXICOL,DEPT BIOCHEM TOXICOL & PATHOL,RES TRIANGLE PK,NC 27709

[3] MERCK SHARP & DOHME RES LABS,DEPT ANIM DRUG METAB,RAHWAY,NJ 07065

来源：

DRUG METABOLISM AND DISPOSITION | 1985年 / 13卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：272 / 275

页数：4

共 50 条

[1] RELATIVE PARTICIPATION OF LIVER MICROSOMAL AMINE OXIDASE AND CYTOCHROME-P-450 IN N-DEMETHYLATION REACTIONS
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ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1977, 180 (02) : 363 - 373
[2] SOURCE OF THE OXYGEN ATOM IN THE PRODUCT OF CYTOCHROME-P-450-CATALYZED N-DEMETHYLATION REACTIONS
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[3] MECHANISMS OF CYTOCHROME-P-450 CATALYZED DENITROSATION REACTIONS
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[4] OXIDATIVE N-DEMETHYLATION OF N,N-DIMETHYLANILINE BY PURIFIED ISOZYMES OF CYTOCHROME-P-450
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[5] THE PEROXIDATIC FUNCTION OF LIVER MICROSOMAL CYTOCHROME-P-450 - COMPARISON OF HYDROGEN-PEROXIDE AND NADPH-CATALYZED N-DEMETHYLATION REACTIONS
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[6] COMPARATIVE-STUDIES OF N-HYDROXYLATION AND N-DEMETHYLATION BY MICROSOMAL CYTOCHROME-P-450
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CHO, AK
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[7] THE ROLE OF CYTOCHROME-P-450 IN THE DUAL PATHWAYS OF N-DEMETHYLATION OF N,N'-DIMETHYLANILINE BY HEPATIC MICROSOMES
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[8] TITRATION OF CATALYTICALLY ACTIVE CENTERS OF RAT HEPATIC MICROSOMAL CYTOCHROME-P-450 WITH METYRAPONE DURING N-DEMETHYLATION REACTIONS
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[9] PARTICIPATION OF CYTOCHROME-P-450 ISOZYMES IN N-DEMETHYLATION, N-HYDROXYLATION AND AROMATIC HYDROXYLATION OF METHAMPHETAMINE
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[10] KINETIC DEUTERIUM-ISOTOPE EFFECTS ON THE N-DEMETHYLATION OF TERTIARY AMIDES BY CYTOCHROME-P-450
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