Glomerulocystic Kidney Disease and Hepatoblastoma in an Infant: A Rare Presentation

被引：1

作者：

Zaman, Rumina ^{[1
]}

Maggi, Alec ^{[2
]}

Rajpoot, Sudeep K. ^{[3
]}

Joshi, Divya-Devi ^{[1
]}

机构：

[1] Miller Childrens & Womens Hosp, Long Beach, CA USA

[2] Drexel Univ, Philadelphia, PA 19104 USA

[3] Amer Univ Antigua, St Johns, Antigua & Barbu

来源：

CASE REPORTS IN NEPHROLOGY AND DIALYSIS | 2015年 / 5卷 / 03期

关键词：

Hepatoblastoma; Beckwith-Wiedemann syndrome; Glomerulocystic kidney disease; Hepatocyte growth factor; Insulin-like growth factors;

D O I：

10.1159/000439520

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Glomerulocystic kidney disease (GCKD) is a rare condition comprising heritable and nonheritable types [Oh et al.: Nephron 1986; 43: 299-302]. Hepatoblastoma is a sporadically occurring tumor of embryonal origin that is associated with overgrowth syndrome and renal cysts. A concurrent presentation of GCKD with hepatoblastoma was first described in 1989 [Rao et al.: Jpn J Surg 1989; 19: 583-585]. We report the simultaneous presentation of hepatoblastoma and GCKD in a 5-month-old child and explore the probability of insulin-like growth factors, insulin-like growth factor-binding protein and Beckwith-Wiedemann gene mutation as a putative cause. (C) 2015 S. Karger AG, Basel

引用

页码：200 / 203

页数：4