SYNTHESIS OF SODIUM [C-11] THIOCYANATE USING [C-11] CYANOGEN-BROMIDE

被引：1

作者：

WESTERBERG, G ^{[1
]}

LANGSTROM, B ^{[1
]}

机构：

[1] UNIV UPPSALA,PET CTR,UAS,S-75185 UPPSALA,SWEDEN

来源：

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 1994年 / 34卷 / 06期

关键词：

C-11]CYANOGEN BROMIDE; SODIUM[C-11]THIOCYANATE; ALKYL[C-11]THIOCYANATES;

D O I：

10.1002/jlcr.2580340608

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A method for the preparation of sodium [C-11]thiocyanate from [C-11]cyanogen bromide and sodium sulfide is described. Sodium [C-11]thiocyanate was obtained in 94% decay-corrected radiochemical yield with a specific radioactivity of 122 GBq mumol-1 (3.3 Ci mumol-1) in a synthesis time of 21 minutes. The sodium [C-11]thiocyanate was used in the synthesis of ethyl-, isopropyl-, and benzyl [C-11]thiocyanate in 78, 71 and 84% radiochemical yields, respectively.

引用

页码：545 / 548

页数：4

共 4 条

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