PRACTICAL TOTAL SYNTHESIS OF (+/-)-STRIGOL

被引：52

作者：

BROOKS, DW

BEVINAKATTI, HS

KENNEDY, E

HATHAWAY, J

机构：

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1985年 / 50卷 / 05期

关键词：

D O I：

10.1021/jo00205a014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An improved total synthesis of racemic strigol [isolated from Gossypium hirsutum and a potent seed germination stimulant for Striga spp.] and 4''-epistrigol from .alpha.-ionone in 10 (4.4% overall yield) or 12 steps (6.8% overall yield) by recycling isomer 16 is described which is applicable on a multigram scale with a minimum of purification steps. The synthetic scheme also allows efficient access to many analogs for the evaluation of structure-activity relationships.

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页码：628 / 632

页数：5

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