PHYTOCHEMICAL SCREENING, TOTAL PHENOLIC AND TOTAL FLAVONOID CONTENT, AND ANTIOXIDANT ACTIVITY OF DIFFERENT PARTS OF Melastoma malabathricum

被引:0
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作者
Danladi, Suleiman [1 ]
Wan-Azemin, Amirah [1 ]
Sani, Yahaya Najib [1 ]
Mohd, Khamsah Suryati [2 ]
Rao, Mahadeva U. S. [1 ]
Mansor, Sharif Mahsufi [3 ]
Dharmaraj, Saravanan [1 ]
机构
[1] Univ Sultan Zainal Abidin, Fac Med, Sch Basic Med Sci, Med Campus, Kuala Terengganu 20400, Terengganu, Malaysia
[2] Univ Sultan Zainal Abidin, Agri Prod & Food Innovat Res Inst AGROPOL, Tembila Campus, Besut 22200, Terengganu, Malaysia
[3] Univ Sains Malaysia, Ctr Drug Res, George Town 11800, Malaysia
来源
关键词
Melastoma malabathricum; DPPH; phenolics; flavonoid; quercetin;
D O I
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中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Melastoma malabathricum Linn. commonly known as 'senduduk' in Malaysia, belongs to Melastomataceae family. The study was carried out to screen the phytochemicals present in methanol extract of leaf, flower, fruit, and stem and to evaluate the antioxidant activity, total flavonoid and total phenolic contents of these different parts. Phytochemical screening showed that all parts of this plant contained tannins, steroids, phenols and flavonoids. The flower extract was found to have highest total phenolic whereas the leaf demonstrated the highest flavonoid content followed by flower. The results of antioxidant activity from the DPPH assay showed that the flower has the highest radical scavenging activity comparable to quercetin standard while stem showed the lowest activity. The higher content of total phenolics, flavonoids and antioxidant capacity of flower suggests the possibility of its incorporation and exclusion of stem in M. malabathricum preparations for development of newer effective drugs.
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页数:6
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