ORGANIZATION AND CHROMOSOMAL LOCALIZATION OF THE GENE (TAF2H) ENCODING THE HUMAN TBP-ASSOCIATED FACTOR-II-30 (TAF(II)30)

被引：11

作者：

SCHEER, E

MATTEI, MG

JACQ, X

CHAMBON, P

TORA, L

机构：

[1] UNIV STRASBOURG 1,COLL FRANCE,INST GENET & BIOL MOLEC & CELLULAIRE,CNRS,INSERM,F-67404 ILLKIRCH GRAFFENS,FRANCE

[2] HOP ENFANTS LA TIMONE,INSERM,U406,F-13385 MARSEILLE 5,FRANCE

[3] HOP ENFANTS LA TIMONE,CTR MED GENET,F-13385 MARSEILLE 5,FRANCE

来源：

GENOMICS | 1995年 / 29卷 / 01期

关键词：

D O I：

10.1006/geno.1995.1243

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The basal RNA polymerase II transcription factor, TFIID, is composed of the TATA binding protein (TBP) and 8-13 TBP-associated factors (TAFs) ranging from 250 to 17 kDa. The structure of the human gene encoding the 30-kDa subunit of TFIID, TAF2H, has been determined. The gene consists of five exons (ranging from 66 to 248 bp) and four introns (ranging from 83 to 211 bp). The transcription start site of the mRNA was mapped, and it shares a weak homology to the consensus of known initiator elements. Using in situ hybridization on human metaphase chromosomes, the TAF2H gene has been localized in the 11p15.2-p15.5 region of the human genome. (C) 1995 Academic Press, Inc.

引用

页码：269 / 272

页数：4

共 23 条

[1] STRUCTURE OF THE GENE ENCODING THE 14.5 KDA SUBUNIT OF HUMAN RNA POLYMERASE-II [J].

ACKER, J ;

WINTZERITH, M ;

VIGNERON, M ;

KEDINGER, C .

NUCLEIC ACIDS RESEARCH, 1993, 21 (23) :5345-5350

[2] DISTINCT TFIID COMPLEXES MEDIATE THE EFFECT OF DIFFERENT TRANSCRIPTIONAL ACTIVATORS [J].

BROU, C ;

CHAUDHARY, S ;

DAVIDSON, I ;

LUTZ, Y ;

WU, J ;

EGLY, JM ;

TORA, L ;

CHAMBON, P .

EMBO JOURNAL, 1993, 12 (02) :489-499

[3] 5 INTERMEDIATE COMPLEXES IN TRANSCRIPTION INITIATION BY RNA POLYMERASE-II [J].

BURATOWSKI, S ;

HAHN, S ;

GUARENTE, L ;

SHARP, PA .

CELL, 1989, 56 (04) :549-561

[4] UNIQUE TATA-BINDING PROTEIN-CONTAINING COMPLEXES AND COFACTORS INVOLVED IN TRANSCRIPTION BY RNA POLYMERASE-II AND POLYMERASE-III [J].

CHIANG, CM ;

GE, H ;

WANG, ZX ;

HOFFMANN, A ;

ROEDER, RG .

EMBO JOURNAL, 1993, 12 (07) :2749-2762

[5] CLONING OF AN INTRINSIC HUMAN TFIID SUBUNIT THAT INTERACTS WITH MULTIPLE TRANSCRIPTIONAL ACTIVATORS [J].

CHIANG, CM ;

ROEDER, RG .

SCIENCE, 1995, 267 (5197) :531-536

[6] PROMOTER SEQUENCES OF EUKARYOTIC PROTEIN-CODING GENES [J].

CORDEN, J ;

WASYLYK, B ;

BUCHWALDER, A ;

CORSI, PS ;

KEDINGER, C ;

CHAMBON, P .

SCIENCE, 1980, 209 (4463) :1406-1414

[7] ROLE OF AN RNA CLEAVAGE POLY(A) ADDITION SITE IN THE PRODUCTION OF MEMBRANE-BOUND AND SECRETED IGM MESSENGER-RNA [J].

DANNER, D ;

LEDER, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (24) :8658-8662

[8] TFD - THE TRANSCRIPTION FACTORS DATABASE [J].

GHOSH, D .

NUCLEIC ACIDS RESEARCH, 1992, 20 :2091-2093

[9] A RELATIONAL DATABASE OF TRANSCRIPTION FACTORS [J].

GHOSH, D .

NUCLEIC ACIDS RESEARCH, 1990, 18 (07) :1749-1756

[10] HUMAN TAF(II)30 IS PRESENT IN A DISTINCT TFIID COMPLEX AND IS REQUIRED FOR TRANSCRIPTIONAL ACTIVATION BY THE ESTROGEN-RECEPTOR [J].

JACQ, X ;

BROU, C ;

LUTZ, Y ;

DAVIDSON, I ;

CHAMBON, P ;

TORA, L .

CELL, 1994, 79 (01) :107-117

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