IDIOPATHIC BRONCHIOLITIS OBLITERANS WITH ORGANIZING PNEUMONIA - AN ACUTE AND LIFE-THREATENING SYNDROME

被引：81

作者：

NIZAMI, IY

KISSNER, DG

VISSCHER, DW

DUBAYBO, BA

机构：

[1] DEPT VET AFFAIRS MED CTR,MED SERV 111A,ALLEN PK,MI 48101

[2] WAYNE STATE UNIV,SCH MED,DEPT MED,DETROIT,MI 48201

[3] WAYNE STATE UNIV,SCH MED,DEPT PATHOL,DETROIT,MI 48201

来源：

CHEST | 1995年 / 108卷 / 01期

关键词：

ACUTE RESPIRATORY FAILURE; BRONCHIOLITIS; CORTICOSTEROIDS; IDIOPATHIC BRONCHIOLITIS OBLITERANS WITH ORGANIZING PNEUMONIA;

D O I：

10.1378/chest.108.1.271

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Idiopathic bronchiolitis obliterans with organizing pneumonia (BOOP) is a clinicopathologic syndrome characterized by an indolent course and favorable prognosis. This report describes five patients with a fulminating and life-threatening variant of this syndrome. Four patients presented with respiratory failure requiring respiratory assistance and positive pressure ventilation. Early recognition of the entity and prompt initiation of corticosteroid therapy in three patients was instrumental in preventing mortality. Our findings suggest that idiopathic BOOP may be the underlying pathology in a number of patients presenting with ARDS. Since corticosteroid therapy may improve survival in these patients, clinicians should heighten their index of suspicion for this entity. Early histologic diagnosis and initiation of corticosteroid therapy should be considered in patients with unexplained ARDS.

引用

页码：271 / 277

页数：7

共 11 条

[1]

Epier GR, Colby TV McLoud, Et al., Bronchiolitis obliterans organizing pneumonia, N Engl J Med, 312, pp. 152-158, (1985)

[2]

Cordier JF, Lorie R, Brune J, Idiopathic bronchiolitis obliterans organizing pneumonia, Chest, 96, pp. 999-1004, (1989)

[3]

King TE, Mortenson RL, Cryptogenic organizing pneumonitis, Chest, 102, pp. 8S-13S, (1992)

[4]

Costabel U, Teschler H, Schoenfeld, BOOP in Europe, Chest, 102, pp. 14S-20S, (1992)

[5]

Yamamoto M, Ina Y, Kitaichi M, Et al., Clinical features of BOOP in Japan, Chest, 102, pp. 21S-25S, (1992)

[6]

Cohen AJ, King TE, Downey GP, Rapidly progressive bronchiolitis obliterans with organizing pneumonia, Am J Respir Crit Care Med, 149, pp. 1670-1675, (1994)

[7]

Bellomo R, Finlay M, McLaughlin P, Et al., Clinical spectrum of cryptogenic organising pneumonitis, Thorax, 46, pp. 554-558, (1991)

[8]

Schwarz MI, Diffuse pulmonary infiltrates and respiratory failure following 2 weeks of dyspnea in a 45-year-old woman, Chest, 104, pp. 927-929, (1993)

[9]

Epler GR, Bronchiolitis obliterans organizing pneumonia: definition and clinical features, Chest, 102, pp. 2S-6S, (1992)

[10]

Epler GR, Colby TV, The spectrum of bronchiolitis obliterans, Chest, 83, pp. 161-164, (1983)

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