Sinus Histiocytosis with Massive Lymphadenopathy (Rosai Dorfman's Disease): A Rare Cause of Lymphadenopathy in Children

Sinus histiocytosis with massive lymphadenopathy also called as Rosai-Dorfman's disease is a benign self limiting rare histiocytic disorder with very few case reports in Pakistani literature. This case report describes a young boy of nine years age who presented with progressive, asymptomatic bilateral cervical lymphadenopathy for eight months. Open cervical lymph node biopsy confirmed the diagnosis on classical histopathological features. As the patient was asymptomatic, we kept him on observation, with follow-up. He shown remarkable reduction in cervical lymphadenopathy.