FREQUENCY AND CHARACTERISTICS OF METABOLIC SYNDROME IN PATIENTS WITH ACUTE CORONARY SYNDROME AMONG PAKISTANI ADULTS

Objective: The aim of our study was to determine the frequency of metabolic syndrome (MS) and to evaluate the distribution of its components in patients with acute coronary syndrome (ACS) among Pakistani adults. Methodology: This descriptive cross sectional study was conducted in Division of cardiovascular medicine and interventional Cardiology, Allama Iqbal Medical College/Jinnah Hospital, Lahore from October 2011 to December 2011. Patients of either gender and from 20 to 75 years of age admitted with ACS via emergency department were recruited after an informed consent. Overall frequency of metabolic syndrome was evaluated in these patients. In addition frequency of individual components of metabolic syndrome as risk factor for acute coronary syndrome was also calculated. Data was analyzed in SPSS version 17. Results: The metabolic syndrome was present in 32% of patients and was more frequent A total of 350 patients with acute coronary syndrome were studied in men than women (75% vs. 25%). The most frequent component of metabolic syndrome as a risk factor for ACS was hypertension seen in 52.6 % patients, followed by diabetes mellitus in 42.8%, abdominal obesity in 41.2%, hypertriglyceridemia in 40.0% and low HDL in 31.7 % of patients. Conclusion: Metabolic syndrome has high frequency in patients with acute coronary syndrome, especially in men. The most frequent components are Hypertension and Diabetes.