DIASTEREOSELECTIVE FLUORINATION OF CHIRAL IMIDE ENOLATES USING N-FLUORO-O-BENZENEDISULFONIMIDE (NFOBS)

被引：91

作者：

DAVIS, FA

HAN, W

机构：

[1] Department of Chemistry, Drexel University, Philadelphia

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 09期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(00)91883-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Alpha-Fluoro acids (78-90% ee) and beta-fluoro alcohols (89- > 95% ee) of well defined stereochemistry are prepared via the diastereoselective fluorination of chiral imide enolates with NFOBS (3).

引用

页码：1153 / 1156

页数：4

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