NOVEL CYTOTOXIC PRINCIPLES OF FORMOSAN GANODERMA-LUCIDUM

被引：94
作者：
LIN, CN
TOME, WP
WON, SJ
机构：
[1] NATL RES INST CHINESE MED,TAIPEI 23177,TAIWAN
[2] NATL CHENG KUNG UNIV,COLL MED,DEPT MICROBIOL,TAINAN 70101,TAIWAN
来源：
JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 04期
关键词：
D O I：
10.1021/np50076a012
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new steryl esters, ergosta-7,22-dien-3-beta-yl linoleate [1] and 5-alpha,8-alpha-epidioxyergosta-6,22-dien-3-beta-yl linoleate [3], and a novel steroid, ergosta-7,22-diene-2-beta,3-alpha,9-alpha-triol [5], have been isolated from the fruiting bodies of Formosan Ganoderma lucidum and characterized. A new lanostanoid, 3-beta-hydroxy-26-oxo-5-alpha-lanosta-8,24-dien-11-one, and the new steroid exhibited potent inhibition of KB cells and human PLC/PRF/5 cells in vitro.
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收藏
页码：998 / 1002
页数：5
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