STIMULATION OF THE GLOBUS-PALLIDUS IN PARKINSONS-DISEASE

被引：36
作者：
IACONO, RP
LONSER, RR
MANDYBUR, G
YAMADA, S
机构：
来源：
BRITISH JOURNAL OF NEUROSURGERY | 1995年 / 9卷 / 04期
关键词：
AKINESIA; GLOBUS PALLIDUS; STIMULATION; PARKINSONS DISEASE;
D O I：
10.1080/02688699550041142
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
In 62 patients undergoing posteroventral pallidotomy (PVP) for the treatment of Parkinson's disease, we have demonstrated significant (p < 0.01) elimination of akinetic features and other symptoms during intraoperative stimulation trials in areas anterior to the PVP target (n = 30). Stimulation in anterior pallidal regions frequently resulted in an immediate reversal of akinetic states despite enforced abstinence of medications. The beneficial effects were achieved with as little as 0.25 V at 100 Hz. Stimulation at the PVP target site (n = 32) resulted in insignificant changes (p > 0.05).
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页码：505 / 510
页数：6
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