DESIGN AND SYNTHESES OF POTENT AND SELECTIVE DIPEPTIDE INHIBITORS OF CANDIDA-ALBICANS MYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE

被引：56

作者：

DEVADAS, B ^{[1
]}

ZUPEC, ME ^{[1
]}

FREEMAN, SK ^{[1
]}

BROWN, DL ^{[1
]}

NAGARAJAN, S ^{[1
]}

SIKORSKI, JA ^{[1
]}

MCWHERTER, CA ^{[1
]}

GETMAN, DP ^{[1
]}

GORDON, JI ^{[1
]}

机构：

[1] WASHINGTON UNIV,SCH MED,DEPT MOLEC BIOL & PHARMACOL,ST LOUIS,MO 63110

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1995年 / 38卷 / 11期

关键词：

D O I：

10.1021/jm00011a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

收藏

页码：1837 / 1840

页数：4

相关论文

共 18 条

[1] CHOW M, 1993, MYRISTOYLATION VIRAL, P59
[2] CHRISTOPHER SJW, 1993, J MED CHEM, V36, P2381
[3] DEVADAS B, 1992, J BIOL CHEM, V267, P7224
[4] DISRUPTION OF THE YEAST N-MYRISTOYL TRANSFERASE GENE CAUSES RECESSIVE LETHALITY
DURONIO, RJ
TOWLER, DA
HEUCKEROTH, RO
GORDON, JI
[J]. SCIENCE, 1989, 243 (4892) : 796 - 800
[5] MUTATIONS OF HUMAN MYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE CAUSE TEMPERATURE-SENSITIVE MYRISTIC ACID AUXOTROPHY IN SACCHAROMYCES-CEREVISIAE
DURONIO, RJ
REED, SI
GORDON, JI
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (09) : 4129 - 4133
[6] HUMAN MYCOSES - DRUGS AND TARGETS FOR EMERGING PATHOGENS
GEORGOPAPADAKOU, NH
WALSH, TJ
[J]. SCIENCE, 1994, 264 (5157) : 371 - 373
[7] GENETIC AND BIOCHEMICAL-STUDIES OF PROTEIN N-MYRISTOYLATION
JOHNSON, DR
BHATNAGAR, RS
KNOLL, LJ
GORDON, JI
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1994, 63 : 869 - 914
[8] KISHORE NS, 1993, J BIOL CHEM, V268, P4889
[9] LODGE JK, 1994, J BIOL CHEM, V269, P2996
[10] TARGETED GENE REPLACEMENT DEMONSTRATES THAT MYRISTOYL-COA/PROTEIN N-MYRISTOYLTRANSFERASE IS ESSENTIAL FOR VIABILITY OF CRYPTOCOCCUS-NEOFORMANS
LODGE, JK
JACKSONMACHELSKI, E
TOFFALETTI, DL
PERFECT, JR
GORDON, JI
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (25) : 12008 - 12012