EFFICACY AND POSSIBLE MECHANISMS OF THE CHINESE HERBS SUCHING-HUO-HSUEI-TANG IN THE TREATMENT OF ADJUVANT-INDUCED ARTHRITIS IN RATS

被引：4

作者：

CHOU, CT

WU, WL

CHANG, ML

CHANG, DM

机构：

[1] Division of Rheumatology-Immunology, China Medical College Hospital, Taichung, Taipei

来源：

AMERICAN JOURNAL OF CHINESE MEDICINE | 1993年 / 21卷 / 02期

关键词：

D O I：

10.1142/S0192415X93000194

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

The Chinese herbal formula Suching-huo-hsuei-tang (SHT) was studied to evaluate its efficacy and possible mechanism on adjuvant - induced arthritis (AIA) in rats. SHT was extracted with water, butanol and chloroform into 5 different layers. The top 3 layers of SHT showed a significant suppression of AIA and writhing reaction; the top 2 layers suppressed neutrophil chemotaxis and platelet aggregation. The results suggest that SHT is very promising in the treatment of rheumatoid arthritis (RA) by way of its anti-inflammatory and analgesic action. The possible mechanisms for arthritis are multifactorial.

引用

页码：159 / 170

页数：12