BRASSICA OLERACEA: PHYTOCHEMICAL PROFILING IN SEARCH FOR ANTICANCER COMPOUNDS

被引：0
作者：
Talreja, Komal [1 ]
Moon, Archana [1 ]
机构：
[1] RTM Nagpur Univ, Univ Dept Biochem, Nagpur 33, Maharashtra, India
来源：
INTERNATIONAL JOURNAL OF LIFE SCIENCE AND PHARMA RESEARCH | 2014年 / 4卷 / 04期
关键词：
Brassica; glucosinolates; phytochemical; Thin layer chromatography (TLC); anticancer;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Phytochemicals are non nutritive, naturally occurring, plant derived chemical compounds having medicinal properties. Genus Brassica contains various phytochemicals like tannins, phlobatannins, terpenoids, flavonoids, glycosides and steroids. The principle component being glucosinolate. Glucosinolates are known to possess antibacterial, antifungal as well as anticancerous activity. In this study, cabbage extract has been investigated for phytochemical screening with special focus on glucosinolates. Glucosinolates are found to be effective against various types of cancer such as breast, lung and colon. Glucosinolates may breakdown to form isothiocyanates and/or nitriles in plants during processing, by the action of the endogenous enzyme myrosinase (thioglucoside glucohydrolase) or within the gastrointestinal tract by the action of commensal microflora.
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页码：L1 / L10
页数：10
相关论文
共 15 条
  • [1] Bazzaz B. S. F., 2005, Iranian Journal of Pharmaceutical Research, V4, P87
  • [2] Bellostas Natalia, 2004, HILMER SORENSEN QUAL, V3
  • [3] Devi JR, 2010, ABR, V4, P309
  • [4] Elliott Malcolm c., ELLIOTT2 BRUCE B STO
  • [5] Emam SS, 2009, J APPL SCI RES, V5, P2315
  • [6] KAMEL A. M., SECONDARY PRIMARY PL
  • [7] nishaa s, 2012, ANTIOXIDANT ACTIVITY, V5
  • [8] Njokul O. Victor, 2009, PLANTS AFRICAN J PUR, V3, P228
  • [9] Ogunwenmo, AFRICAN J BIOTECHNOL, V9, P4880
  • [10] Patel Avani, 2010, LEGUMINOSAE INT J PH, V1, P66
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