2-DIMENSIONAL H-1-NMR SPECTROSCOPY OF NORMAL AND PATHOLOGICAL HUMAN PLASMA - COMPLETE WATER SUPPRESSION AND FURTHER ASSIGNMENT OF RESONANCES

被引：8

作者：

KRIAT, M ^{[1
]}

CONFORTGOUNY, S ^{[1
]}

VIONDURY, J ^{[1
]}

VIOUT, P ^{[1
]}

COZZONE, PJ ^{[1
]}

机构：

[1] FAC MED MARSEILLE,CNRS,URA 1186,CTR RESONANCE MAGNET BIOL & MED,27 BD J MOULIN,F-13005 MARSEILLE,FRANCE

来源：

BIOCHIMIE | 1992年 / 74卷 / 9-10期

关键词：

H-1 2-D NMR; HUMAN PLASMA; FUCOSYLATED LIPIDS; CANCER;

D O I：

10.1016/0300-9084(92)90075-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two-dimensional J-resolved and correlated H-1 NMR spectra with complete water suppression have been obtained to further characterize a metabolic pattern for normal and pathological human plasma samples. H-1 COSY spectra have been recorded on plasma from 12 patients with cancer in order to check for the possible presence of fucose. Our results show that there is no evidence for the presence of fucosylated lipids in the plasma of these patients.

引用

页码：913 / 918

页数：6

共 17 条

[1] BALES JR, 1985, CLIN CHEM, V31, P757
[2] METABOLIC PROFILING OF BODY-FLUIDS BY PROTON NMR - SELF-POISONING EPISODES WITH PARACETAMOL (ACETAMINOPHEN)
BALES, JR
BELL, JD
NICHOLSON, JK
SADLER, PJ
TIMBRELL, JA
HUGHES, RD
BENNETT, PN
WILLIAMS, R
[J]. MAGNETIC RESONANCE IN MEDICINE, 1988, 6 (03) : 300 - 306
[3] BARCLAY M, 1970, CANCER RES, V30, P2420
[4] NMR-INVISIBLE LACTATE IN BLOOD-PLASMA
BELL, JD
BROWN, JCC
KUBAL, G
SADLER, PJ
[J]. FEBS LETTERS, 1988, 235 (1-2) : 81 - 86
[5] CHEMICAL-EXCHANGE AND PARAMAGNETIC-T2 RELAXATION AGENTS FOR WATER SUPPRESSION IN SPIN-ECHO PROTON NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY OF BIOLOGICAL-FLUIDS
CONNOR, S
NICHOLSON, JK
EVERETT, JR
[J]. ANALYTICAL CHEMISTRY, 1987, 59 (24) : 2885 - 2891
[6] KRIAT M, 1991, PRESSE MED, V20, P852
[7] KRIAT M, 1990, 7TH ANN C STASB
[8] FUCOSE IN H-1 COSY SPECTRA OF PLASMA-MEMBRANE FRAGMENTS SHED FROM HUMAN-MALIGNANT COLORECTAL CELLS
LEAN, CL
MACKINNON, WB
MOUNTFORD, CE
[J]. MAGNETIC RESONANCE IN MEDICINE, 1991, 20 (02) : 306 - 311
[9] MOUNTFORD CE, 1987, LANCET, V1, P829
[10] HIGH-RESOLUTION PROTON MAGNETIC-RESONANCE SPECTROSCOPY OF BIOLOGICAL-FLUIDS
NICHOLSON, JK
WILSON, ID
[J]. PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY, 1989, 21 (pt 4-5) : 449 - 501

← 1 2 →