CAN LINOLEIC-ACID CONTRIBUTE TO CORONARY-ARTERY DISEASE

被引：87
作者：
HODGSON, JM
WAHLQVIST, ML
BOXALL, JA
BALAZS, ND
机构：
[1] MONASH UNIV,MONASH MED CTR,DEPT MED,CLAYTON RD,CLAYTON,VIC 3168,AUSTRALIA
[2] MONASH MED CTR,DEPT CARDIOL,MELBOURNE,AUSTRALIA
[3] MONASH MED CTR,DEPT CLIN BIOCHEM,MELBOURNE,AUSTRALIA
来源：
AMERICAN JOURNAL OF CLINICAL NUTRITION | 1993年 / 58卷 / 02期
关键词：
LINOLEIC ACID; OMEGA-3 FATTY ACIDS; POLYUNSATURATED FATTY ACIDS; CORONARY ARTERY DISEASE; ATHEROSCLEROSIS;
D O I：
10.1093/ajcn/58.2.228
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
The adipose tissue concentration of linoleic acid was positively associated with the degree of coronary artery disease (CAD) in a cross-sectional study of 226 patients undergoing coronary angiography. Linoleic acid concentration in adipose tissue is known to reflect the intake of this fatty acid. These results are therefore indicative of a positive relationship between linoleic acid intake and CAD. The platelet linoleic acid concentration was also positively associated with CAD. After confounding factors were allowed for, the eicosapentaenoic acid concentration in platelets was inversely associated with CAD for men, and the docosapentaenoic acid concentration in platelets was inversely associated with CAD for women; results consistent with several other studies that suggest that fish, and omega-3 fatty acids derived from fish and fish oils, can beneficially influence macrovascular disease.
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页码：228 / 234
页数：7
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