EXCITATORY AMINO-ACIDS AND THE ACTIONS OF COCAINE

被引：72
|
作者：
KARLER, R
CALDER, LD
机构：
[1] Department of Pharmacology, University of Utah School of Medicine, Salt Lake City
来源：
BRAIN RESEARCH | 1992年 / 582卷 / 01期
关键词：
COCAINE; EXCITATORY AMINO ACID; GLUTAMATE; N-METHYL-D-ASPARTATE; DOPAMINE; CONVULSION; ANIMAL;
D O I：
10.1016/0006-8993(92)90329-8
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Antagonists of the N-methyl-D-aspartate (NMDA) type of excitatory amino acid (EAA) receptors blocked cocaine-induced stereotypy, locomotor stimulation and convulsions. These effects in general appear to involve selectively NMDA type of receptors. The results suggest that NMDA-activated systems are an integral component in the reaction sequences involved in the expression of several behavioral effects of cocaine.
引用
收藏
页码：143 / 146
页数：4
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