CONSTRUCTION AND EVALUATION OF THE KINETIC SCHEME ASSOCIATED WITH DIHYDROFOLATE-REDUCTASE FROM ESCHERICHIA-COLI

被引：472

作者：

FIERKE, CA ^{[1
]}

JOHNSON, KA ^{[1
]}

BENKOVIC, SJ ^{[1
]}

机构：

[1] PENN STATE UNIV, DEPT CHEM, UNIVERSITY PK, PA 16802 USA

来源：

BIOCHEMISTRY | 1987年 / 26卷 / 13期

关键词：

D O I：

10.1021/bi00387a052

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：4085 / 4092

页数：8

共 43 条

[1] ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE - ISOLATION AND CHARACTERIZATION OF 2 ISOZYMES
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[2] ANALYSIS OF NUMERICAL-METHODS FOR COMPUTER-SIMULATION OF KINETIC PROCESSES - DEVELOPMENT OF KINSIM - A FLEXIBLE, PORTABLE SYSTEM
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[J]. ANALYTICAL BIOCHEMISTRY, 1983, 130 (01) : 134 - 145
[3] BINDING OF COENZYME ANALOGS TO LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE - BINARY AND TERNARY COMPLEXES
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[J]. BIOCHEMISTRY, 1980, 19 (16) : 3723 - 3731
[4] NEGATIVE COOPERATIVITY BETWEEN FOLINIC ACID AND CO-ENZYME IN THEIR BINDING TO LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE
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[J]. BIOCHEMISTRY, 1981, 20 (25) : 7186 - 7195
[5] ROLE OF ISOMERIZATION OF INITIAL COMPLEXES IN THE BINDING OF INHIBITORS TO DIHYDROFOLATE-REDUCTASE
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[J]. BIOCHEMISTRY, 1985, 24 (18) : 4772 - 4777
[6] CRYSTALLINE DIHYDROPTEROYLGLUTAMIC ACID
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[J]. NATURE, 1960, 188 (4746) : 231 - 232
[7] BLAKLEY RL, 1985, BIOCHEMISTRY-US, V24, P4704, DOI 10.1021/bi00338a032
[8] BOLIN JT, 1982, J BIOL CHEM, V257, P13650
[9] KINETICS OF SUBSTRATE, COENZYME, AND INHIBITOR BINDING TO ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE
CAYLEY, PJ
DUNN, SMJ
KING, RW
[J]. BIOCHEMISTRY, 1981, 20 (04) : 874 - 879
[10] SITE-SPECIFIC MUTAGENESIS OF DIHYDROFOLATE-REDUCTASE FROM ESCHERICHIA-COLI
CHEN, JT
MAYER, RJ
FIERKE, CA
BENKOVIC, SJ
[J]. JOURNAL OF CELLULAR BIOCHEMISTRY, 1985, 29 (02) : 73 - 82

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