EPOXIDATION OF FLAVONES BY DIMETHYLDIOXIRANE

被引：51

作者：

ADAM, W ^{[1
]}

GOLSCH, D ^{[1
]}

HADJIARAPOGLOU, L ^{[1
]}

PATONAY, T ^{[1
]}

机构：

[1] LAJOS KOSSUTH UNIV,DEPT ORGAN CHEM,H-4010 DEBRECEN,HUNGARY

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 26期

关键词：

D O I：

10.1021/jo00026a020

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of epoxides 2 by epoxidation of flavones 1 with isolated dimethyldioxirane (as acetone solution) at subambient temperatures is reported. These labile epoxides were isolated and completely characterized by UV, IR, H-1 and C-13 NMR, MS, and C, H analyses. Warming to room temperature led to rearrangement to afford quantitatively the 3-hydroxyflavones 3b,h,i,n. Treatment of the epoxides 2b,f with methanol led to the 3-hydroxy-2-methoxyflavanones 4b,f as a mixture of cis and trans isomers.

引用

页码：7292 / 7297

页数：6

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