STEREOTAXIC RADIOTHERAPY OF MALIGNANCIES IN THE ABDOMEN - METHODOLOGICAL ASPECTS

被引:397
作者
LAX, I
BLOMGREN, H
NASLUND, I
SVANSTROM, R
机构
[1] KAROLINSKA HOSP,DEPT ONCOL,S-10401 STOCKHOLM,SWEDEN
[2] KAROLINSKA HOSP,DEPT DIAGNOST RADIOL,S-10401 STOCKHOLM,SWEDEN
关键词
D O I
10.3109/02841869409121782
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A method for sterotactic high-dose radiotherapy of malignancies in the abdomen has been developed. A stereotactic frame for the body has been developed and a method for fixation of the patient in the frame is described. The reproducibility in the stereotactic system of tumours in the liver and the lung was found to be within 5-8 mm for 90% of the patient set-ups. The diaphragmatic movements were reduced to 5-10 mm, by applying a pressure on the abdomen. An analytical method is used to calculate dose distributions for a continuum of beams in an isocentric treatment technique. The advantage of a heterogeneous target dose is demonstrated and proposed for the present application. A non-coplanar treatment technique, using eight individually shaped beams is proposed and has been used for patient treatments. The dose distribution for a patient with a metastasis in the liver is shown as well as dose volume histograms for the target and the liver.
引用
收藏
页码:677 / 683
页数:7
相关论文
共 11 条
[1]   TISSUE TOLERANCE OF NORMAL AND SURGICALLY MANIPULATED CANINE LIVER TO INTRAOPERATIVE RADIATION-THERAPY (IORT) [J].
CROMHEECKE, M ;
VERMEIJ, J ;
GROND, AJK ;
KONINGS, AWT ;
OLDHOFF, J ;
HOEKSTRA, HJ .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1993, 27 (05) :1141-1146
[2]   TOLERANCE OF NORMAL TISSUE TO THERAPEUTIC IRRADIATION [J].
EMAMI, B ;
LYMAN, J ;
BROWN, A ;
COIA, L ;
GOITEIN, M ;
MUNZENRIDER, JE ;
SHANK, B ;
SOLIN, LJ ;
WESSON, M .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1991, 21 (01) :109-122
[3]  
Fowler JF., 1992, SEMIN RADIAT ONCOL, V2, P16, DOI 10.1016/S1053-4296(05)80045-1
[4]   A COMPARISON OF TECHNIQUES FOR STEREOTAXIC RADIOTHERAPY BY LINEAR-ACCELERATOR BASED ON 3-DIMENSIONAL DOSE DISTRIBUTIONS [J].
GRAHAM, JD ;
NAHUM, AE ;
BRADA, M .
RADIOTHERAPY AND ONCOLOGY, 1991, 22 (01) :29-35
[5]   CONCOMITANT BOOST RADIOTHERAPY FOR ADVANCED SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK [J].
KNEE, R ;
FIELDS, RS ;
PETERS, LJ .
RADIOTHERAPY AND ONCOLOGY, 1985, 4 (01) :1-7
[6]   STEREOTAXIC RADIOTHERAPY OF IRREGULAR TARGETS - A COMPARISON BETWEEN STATIC CONFORMAL BEAMS AND NONCOPLANAR ARCS [J].
LAING, RW ;
BENTLEY, RE ;
NAHUM, AE ;
WARRINGTON, AP ;
BRADA, M .
RADIOTHERAPY AND ONCOLOGY, 1993, 28 (03) :241-246
[7]   THE RADIOBIOLOGY OF RADIOSURGERY [J].
LARSON, DA ;
FLICKINGER, JC ;
LOEFFLER, JS .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1993, 25 (03) :557-561
[8]   THE USE OF 3-D-DOSE VOLUME ANALYSIS TO PREDICT RADIATION HEPATITIS [J].
LAWRENCE, TS ;
TENHAKEN, RK ;
KESSLER, ML ;
ROBERTSON, JM ;
LYMAN, JT ;
LAVIGNE, ML ;
BROWN, MB ;
DUROSS, DJ ;
ANDREWS, JC ;
ENSMINGER, WD ;
LICHTER, AS .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1992, 23 (04) :781-788
[9]   TARGET DOSE VERSUS EXTRATARGET DOSE IN STEREOTAXIC RADIOSURGERY [J].
LAX, I .
ACTA ONCOLOGICA, 1993, 32 (04) :453-457
[10]   THE SIMULTANEOUS BOOST TECHNIQUE - THE CONCEPT OF RELATIVE NORMALIZED TOTAL DOSE [J].
LEBESQUE, JV ;
KEUS, RB .
RADIOTHERAPY AND ONCOLOGY, 1991, 22 (01) :45-55