FAMILIAL IGA NEPHROPATHY ASSOCIATED WITH BILATERAL SENSORINEURAL DEAFNESS

被引：4

作者：

CHAHIN, J

ORTIZ, A

MENDEZ, L

GALLEGO, E

GARCIAPEREZ, J

GARCIACASTRO, G

JULIAN, BA

EGIDO, J

机构：

[1] FDN JIMENEZ DIAZ,SERV NEFROL,AV REYES CATOLICOS 2,E-28040 MADRID,SPAIN

[2] HOSP NTRA SRA LE CANDELARIA,SERV NEFROL,TENERIFE,SPAIN

[3] HOSP UNIV TENERIFE,SERV ANAT PATOL,TENERIFE,SPAIN

[4] UNIV ALABAMA,DEPT MED,DIV NEPHROL,BIRMINGHAM,AL 35294

来源：

AMERICAN JOURNAL OF KIDNEY DISEASES | 1992年 / 19卷 / 06期

关键词：

IGA NEPHROPATHY; SENSORINEURAL DEAFNESS; FAMILIAL; HEMATURIA;

D O I：

10.1016/S0272-6386(12)80840-7

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Alport’s syndrome is the most frequent disorder with familial nephritis and deafness, but other types of nephropathy have been occasionally associated with hereditary hearing loss. The familial occurrence of IgA nephropathy has been well documented. We report a family with hereditary, bilateral, sensorineural deafness spanning four generations. Three of five members with deafness had microscopic hematuria. Renal histology of the two deaf members undergoing biopsy showed mesangial glomerulonephritis with mesangiallgA deposits, without ultrastructural abnormalities of the glomerular basement membranes. Familial nephritis with deafness should not be equated with the diagnosis of Alport’s syndrome. © 1992, National Kidney Foundation. All rights reserved.. All rights reserved.

引用

页码：592 / 596

页数：5

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[2]

BIZZARRI D, 1990, CONTRIB NEPHROL, V80, P113

[3]

CAMERON JS, 1990, PATHOGENESIS IGA NEP, P147

[4] IMMUNOLOGICAL ABNORMALITIES IN HEALTHY RELATIVES OF PATIENTS WITH IGA NEPHROPATHY [J].